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Once-weekly semaglutide 2.4 mg led to significant decreases in body weight and fat mass over 12 months while preserving lean mass and improved muscle function in adults with obesity. Weight and fat
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In the OASIS 4 phase 3 trial, once-daily oral semaglutide at a dose of 25 mg resulted in a greater mean reduction in body weight than placebo in participants with overweight or
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